Psilocybin-Assisted Therapy: A Modern Approach to Mental Health
Where ancient wisdom meets evidence-based mental health care.
For thousands of years, cultures around the world have worked with psilocybin mushrooms for healing, insight, and spiritual growth. Today, Colorado stands at the forefront of bringing this tradition into regulated therapeutic practice. With the passage of the Natural Medicine Act (Proposition 122) in 2022 and the opening of licensed healing centers in 2025, Psychedelic Therapy Den is proud to offer psilocybin-supported services under full regulatory compliance with the Colorado Department of Regulatory Agencies – creating a safe, structured, and intentional setting for healing.
The Therapeutic Potential of Psilocybin
Traditional mental health treatments don’t always go far enough.
Many people reach a point where standard medications or talk therapy feel limited, leaving them stuck with unresolved patterns or discouraging symptoms. Psilocybin offers a fundamentally different therapeutic experience – one rooted in natural medicine and supported by growing clinical research.
Studies funded by the National Institutes of Health have shown promising outcomes for psilocybin in areas such as addiction, treatment-resistant depression, and psychological distress in patients facing serious illness. At Psychedelic Therapy Den, we’ve seen how guided psilocybin sessions – conducted responsibly and within Colorado’s regulatory framework – can help people access insight, emotional relief, and a renewed sense of wellbeing.
The Science Behind the Medicine
Psilocybin is a naturally occurring, non-habit-forming psychedelic compound found in certain mushroom species.
When taken in a therapeutic setting, it temporarily shifts consciousness in ways that can support emotional insight, expanded awareness, and meaningful personal reflection. Experiences often include enhanced mood, increased sensory perception, and changes in thought patterns. A typical session lasts between two and six hours, depending on individual dosing and physiology.
The modern scientific interest in psilocybin accelerated after a landmark 2006 study at Johns Hopkins University demonstrated both its safety profile and the potential for long-lasting positive effects following a single guided dose. Since then, research has expanded worldwide, examining applications for treatment-resistant depression, trauma-related conditions, tobacco and alcohol use disorders, and anxiety—especially in individuals facing serious illness. With each new study, the evidence base for psilocybin-assisted therapy continues to grow.
Prioritizing Your Well-Being
Guiding someone through an expanded state of consciousness requires clinical skill, presence, and a commitment to safety.
At Psychedelic Therapy Den, your physical and emotional wellbeing is at the center of everything we do. Michael P. Biggans, JD/MS, LPC/LCPF, along with all collaborating facilitators, hold active licensure with the Colorado Department of Regulatory Agencies and bring extensive training and experience in psychedelic-assisted care.
Clinical research consistently shows that psilocybin has a strong safety profile when administered in a structured, supervised setting. That said, certain mental health histories—particularly schizophrenia spectrum and/or psychotic disorders—may indicate that psilocybin is not appropriate. We encourage all prospective clients to speak with their physician, especially if they have medical conditions, take prescription medications, or have questions about whether psilocybin is a good fit for their situation.
Determining If This Path Suits You
Emerging research shows that psilocybin-assisted therapy may support healing across a wide range of mental, emotional, and psychosomatic conditions.
Clinical studies and practitioner reports suggest potential benefits for persistent depression, anxiety, trauma-related symptoms, substance dependence, and certain stress-related physical concerns such as headaches, digestive issues, and urinary symptoms. These challenges are often linked to unresolved emotional patterns, chronic stress, or misalignment with personal values. Beyond symptom relief, many clients report meaningful insight, emotional clarity, a deeper sense of connection, and lasting perspective shifts that support long-term wellbeing.
Psilocybin-assisted therapy is not appropriate for everyone. We use a thorough intake and screening process to determine whether this approach aligns with your goals and health history. In some cases—particularly when medical conditions or medications are involved—we may request written clearance from your physician. This process reflects our commitment to safe, ethical, and client-centered care, with your primary care provider remaining the best resource for medical guidance.
Our Psychedelic Therapy Practice
Comprehensive Psilocybin Therapy in Colorado
At Psychedelic Therapy Den, we provide full-spectrum psilocybin-assisted therapy services, including preparation sessions, guided psilocybin administration, and post-session integration.
Michael P. Biggans, JD/MS, LPC/LCPF, is a licensed psychedelic facilitator in Colorado with expertise in supporting clients facing complex mental health challenges and chronic conditions that have not responded to conventional treatments, including anxiety, depression, PTSD, and OCD.
Accessible and Inclusive Care: We are committed to making psychedelic therapy in Denver and Colorado accessible. Reduced-rate sessions are available for clients with financial constraints, and training rates are offered for students or emerging facilitators. Availability can be discussed during your initial free consultation.
What to Expect
Your therapeutic journey unfolds through collaboration between you & your facilitator. Each experience is uniquely tailored.
Initial Consultation
Schedule a no-cost exploratory call with our lead Clinician Michael P. Biggans. We’ll address your questions, discuss whether this modality fits your needs, and if you choose to proceed, pair you with a licensed facilitator whose approach aligns with your objectives.
Preparation Phase
You’ll meet with your facilitator at least once, no fewer than 24 hours before your psilocybin session. These meetings explore your personal history, clarify your intentions, and establish the framework for your experience. Sessions occur in-person or remotely based on your preference. Questions are always welcome—this is a collaborative process.
Session Day
Arriving at our center, your facilitator will orient you to the space before you settle into your private room. By this point, you’ll have agreed upon dosage, duration, and comfort protocols. Our team’s sole focus during your time with us is ensuring you feel safe, supported, and cared for throughout the journey.
Integration Work
These conversations help you make meaning of your experience and translate insights into tangible life changes. Some clients benefit most from multiple sessions with integration between each journey, which can be added for the regular cost of each facilitator’s private practice rate.
Legal and Medical Framework
Colorado’s regulatory structure differs from traditional medical models. You don’t need a prescription or physician referral to access psilocybin therapy. State law does require preparation work with a licensed facilitator before any psilocybin is consumed.
Certain medical situations require documented physician approval before Psychedelic Therapy Den can provide services. These include histories of psychotic episodes, current treatment with antipsychotic medications or specific antidepressants (SSRIs), and significant cardiovascular or kidney conditions. This isn’t optional—we’re legally prohibited from proceeding without proper medical authorization when these factors are present. These safeguards exist to protect you.
Continue reading to learn more or feel free to reach out to us below on a secure contact form. Together, we’ll determine whether psilocybin-assisted therapy represents the right next step in your healing journey.